Molecular Mechanisms Underlying the Chemosensory-mediated Enhanced Acceptance of Ethanol as a Consequence of Prenatal Exposure
|Date(s)|| 02/18/2013 - 4:00 p.m.
|Location||Donahue Auditorium, Gordon Science Center|
|Presenter||Laura Prestia, Ph.D. Candidate, Department of Psychiatry, SUNY Upstate Medical University|
|Description|| Abstract: Human and animal studies demonstrate multiple negative effects of prenatal ethanol exposure on postnatal development. Among these include the increased probability of postnatal ethanol preference that can lead to drug addiction. Previously, we demonstrated that prenatal exposure increased adolescent ethanol intake and this effect was mediated, in part, by enhanced olfactory behavior tuned to ethanol, and increased oral acceptability of ethanol’s specific aversive flavor attributes, bitter and oral irritation. Without further ethanol exposure, these behavioral alterations normalized by adulthood. We are currently investigating the underlying molecular basis for increased ethanol avidity and oral acceptability stemming from prior fetal ethanol exposure.
The Asa Gray Seminar Series is sponsored by the Asa Gray Biological Society, and is the longest running seminar series at Utica College. Scientists are invited from throughout the region to present seminars on their ongoing research.
All lectures are held in Donahue Auditorium, Gordon Science Center, at 4:00 p.m. An informal reception immediately follows. Call (315) 792-3028 for more information.
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